Article

A comparison of humans and baboons suggests germline mutation rates do not track cell divisions

2019-11-16

Abstract excerpt

In humans, most germline mutations are inherited from the father. This observation is widely interpreted as resulting from the replication errors that accrue during spermatogenesis. If so, the male bias in mutation should be substantially lower in a closely related species with similar rates of spermatogonial stem cell divisions but a shorter mean age of reproduction. To test this hypothesis, we resequenced two 3–...

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Literature Corpus work: 64a47eba-3825-5d48-b020-943f99c65957
DOI: 10.1101/844910

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