Article

Clair: Exploring the limit of using a deep neural network on pileup data for germline variant calling

2019-12-05

Abstract excerpt

Single-molecule sequencing technologies have emerged in recent years and revolutionized structural variant calling, complex genome assembly, and epigenetic mark detection. However, the lack of a highly accurate small variant caller has limited the new technologies from being more widely used. In this study, we present Clair, the successor to Clairvoyante, a program for fast and accurate germline small variant call...

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Identifiers and source

Literature Corpus work: 649efc9b-0303-5d60-826b-e22e724f941e
DOI: 10.1101/865782

Open publication

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