Article

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis

2018-09-11

Abstract excerpt

Background \nGlycated hemoglobin (HbA1c) is used to diagnose type 2 diabetes (T2D) and assess glycemic control in patients with diabetes. Previous genome-wide association studies (GWAS) have identified 18 HbA1c-associated genetic variants. These variants proved to be classifiable by their likely biological action as erythrocytic (also associated with erythrocyte traits) or glycemic (associated with other glucose-r...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 55d93af2-6784-569e-a1ec-fefa9bb2008d
DOI: 10.1530/ey.15.13.14

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysisDOI 10.1530/ey.15.13.14Read

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.Semantic proximity Read

Impact of Genetic Determinants of HbA1c on Type 2 Diabetes Risk and Diagnosis.Semantic proximity Read

Impact of rare and common genetic variants on diabetes diagnosis by hemoglobin A1c in multi-ancestry cohorts: The Trans-Omics for Precision Medicine ProgramSemantic proximity Read

Hemoglobin A1c Genetics and Disparities in Risk of Diabetic Retinopathy in Individuals of Genetically Inferred African American/African British and European AncestriesSemantic proximity Read

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways.Semantic proximity Read

A Genome-Wide Association Study Identifies Blood Disorder–Related Variants Influencing Hemoglobin A1c With Implications for Glycemic Status in U.S. Hispanics/LatinosSemantic proximity Read

Genetic determinants of variability in glycated hemoglobin (HbA(1c)) in humans: review of recent progress and prospects for use in diabetes care.Semantic proximity Read

The trans-ancestral genomic architecture of glycemic traits.Semantic proximity Read

HbA1c Levels Are Genetically Determined Even in Type 1 DiabetesSemantic proximity Read

Genetics and its potential to improve type 1 diabetes care.Semantic proximity Read

Clinical and research uses of genetic risk scores in type 1 diabetes.Semantic proximity Read

Recent advances in understanding the genetic architecture of type 2 diabetes.Semantic proximity Read