Article

Dexamethasone and IFN-γ primed mesenchymal stem cells conditioned media immunomodulates aberrant NETosis in SLE via PGE2 and IDO

2024-06-19

Abstract excerpt

<title>Abstract</title> <p>Background Systemic Lupus Erythematosus (SLE) is characterized by dysregulated immune responses, with neutrophil extracellular traps (NETs) playing a significant role. NETs are recognized by autoantibodies in SLE patients, exacerbating pathology. Both excessive NET formation and impaired degradation contribute to SLE pathophysiology. Objective To investigate the immunomodulatory effec...

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Literature Corpus work: 640fb3d1-18ca-5ee8-841f-87f0f512bc94
DOI: 10.21203/rs.3.rs-4538464/v1

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