Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Neutrophil Extracellular Trap Mitochondrial DNA and Its Autoantibody in Systemic Lupus Erythematosus and a Proof‐of‐Concept Trial of Metformin

5 Aug 2015

Abstract excerpt

OBJECTIVE: Neutrophil extracellular traps (NETs) have been shown to play an important role in systemic lupus erythematosus (SLE) pathogenesis by activating plasmacytoid dendritic cells (PDCs) and the type I interferon (IFN) pathway. NETs composed of self-DNA are considered to be of nuclear origin and are a major source of anti-DNA autoantibody generation. This study was undertaken to evaluate whether...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Adhesion Molecules Research
Share to Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Share to Systemic Lupus Erythematosus Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26245802
DOI: 10.1002/art.39296

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Neutrophil Extracellular Trap Mitochondrial DNA and Its Autoantibody in Systemic Lupus Erythematosus and a Proof‐of‐Concept Trial of MetforminPMID 26245802Read ↗

Characterization of anti-neutrophil extracellular traps (NET) antibodies according to systemic lupus erythematosus clinical phenotypes.Semantic proximity Read ↗

Mitochondrial aberrations in systemic lupus erythematosus pathogenesis: Insights and therapeutic implicationsSemantic proximity Read ↗

Mitochondria as a key player in systemic lupus erythematosusSemantic proximity Read ↗

Anti-mitochondrial autoantibodies in systemic lupus erythematosus and their association with disease manifestationsSemantic proximity Read ↗

Neutrophils impair B cell differentiation via mitochondrial and lipid metabolism in lupusSemantic proximity Read ↗

Autoantibodies in Systemic Lupus Erythematosus Target Mitochondrial RNASemantic proximity Read ↗

Neutrophil Extracellular Traps-DNase Balance and Autoimmunity.Semantic proximity Read ↗

Neutrophil Extracellular Traps Participate in the Pathogenesis of Lupus Through S100A10‐Mediated Regulatory T‐Cell Differentiation and Functional AbnormalitiesSemantic proximity Read ↗

Mitochondrial DNA damage is associated with damage accrual and disease duration in patients with Systemic Lupus ErythematosusSemantic proximity Read ↗

An Emerging Role for Anti-DNA Antibodies in Systemic Lupus ErythematosusSemantic proximity Read ↗

The Role of the Oxidative State and Innate Immunity Mediated by TLR7 and TLR9 in Lupus NephritisSemantic proximity Read ↗

NCF1-339 polymorphism is associated with altered formation of neutrophil extracellular traps, high serum interferon activity and antiphospholipid syndrome in systemic lupus erythematosus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.