Article

Metabolic reprogramming underlies cavefish muscular endurance despite loss of muscle mass and contractility

2022-03-14

Abstract excerpt

Physical inactivity – specifically the lack of moderate-to-vigorous activity – is a scourge to human health, promoting metabolic disease and muscle wasting. Interestingly, multiple ecological niches have relaxed investment into physical activity, providing unique evolutionary insight into adaptive physical inactivity. The Mexican cavefish Astyanax mexicanus lost moderate-to-vigorous activity following cave coloni...

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Literature Corpus work: 63d97d96-3881-58e4-8ea7-de175df5338b
DOI: 10.1101/2022.03.12.484091

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