Article

SARS-CoV-2-induced dysregulation in ADAR editing patterns persists post viral clearance in individuals with mild COVID-19

2025-06-11

Abstract excerpt

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections remain a public health concern worldwide. Viral antigen triggered innate immune response leads to induction of interferons (IFNs) and interferon stimulated genes (ISGs) including ADAR1 p150 isoform, which edits adenosine (A) residues within double stranded RNAs in both the virus and the host. Such RNA editing mediated by ADARs plays a crucial...

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Literature Corpus work: 265a507f-f7eb-5aa3-b263-119633537271
DOI: 10.1101/2025.06.09.658648

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