Article

Gene therapy for alopecia in type II rickets model rats using vitamin D receptor-expressing adenovirus vector

2023-04-26

Abstract excerpt

Type II rickets is a hereditary disease caused by a mutation in the vitamin D receptor (VDR) gene. The main symptoms of this disease are bone dysplasia and alopecia. Bone dysplasia can be ameliorated by high calcium intake; however, there is no suitable treatment for alopecia. In this study, we verified whether gene therapy using an adenoviral vector (AdV) had a therapeutic effect on alopecia in Vdr -KO rats. The...

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Literature Corpus work: 635919d2-7f65-5242-bbcb-4a05cad97851
DOI: 10.21203/rs.3.rs-2830029/v1

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