Article

Mice with mutations in Trpm1, a gene within the locus of 15q13.3 microdeletion syndrome, display pronounced hyperactivity and decreased anxiety-like behavior.

2021-02-01

Abstract excerpt

15q13.3 microdeletion syndrome is a genetic disorder caused by a deletion of a region containing seven genes on chromosome 15, MTMR10 , FAN1 , TRPM1 , MIR211 , KLF13 , OTUD7A , and CHRNA7 , and characterized by a wide spectrum of psychiatric disorders. The contribution of each gene in this syndrome has been studied using mutant mouse models, but no single mouse model recapitulates the whole spectrum of human 15q13...

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Literature Corpus work: 635478a9-5b0a-5b4f-86a4-cba3d611d74f
DOI: 10.21203/rs.3.rs-122647/v2

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