Article

Region-specific Brain Targets Drive Circuit Formation and Maturation of Human Retinal Ganglion Cells

2025-05-10

Abstract excerpt

Human vision relies on retinal ganglion cells (RGCs), and their connectivity with distinct brain regions enables higher order visual processing. RGCs vary considerably between species, and many model organisms display distinct RGC types and innervation patterns from those in humans. There is thus a need for robust models of human RGC circuit formation that preserves innervation specificity. Here, we developed an...

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Literature Corpus work: 633c51d3-edf0-59d6-8a67-165fbbaba277
DOI: 10.1101/2025.05.10.651091

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