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Whole blood transcriptome analysis in amyotrophic lateral sclerosis: A biomarker study

25 Jun 2018

Abstract excerpt

The biological pathways involved in amyotrophic lateral sclerosis (ALS) remain elusive and diagnostic decision-making can be challenging. Gene expression studies are valuable in overcoming such challenges since they can shed light on differentially regulated pathways and may ultimately identify valuable biomarkers. This two-stage transcriptome-wide study, including 397 ALS patients and 645 control subjects,...

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PMID: 29939990
DOI: 10.1371/journal.pone.0198874

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