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The methylation of the RANKL/OPG system is involved in fluorosis, and the effect of betaine supplementation

2026-03-26

Abstract excerpt

<title>Abstract</title> <p> Objective This study aims to explore the role of DNA methylation in the promoter region of the RANKL/OPG on fluorosis and the effect of betaine supplementation. Methods A case-control study of 82 paired cases and controls was conducted among residents in coal-burning fluorosis areas in Guizhou Province, China. In addition, 60 SD rats were randomly divided into five groups (n = 12):...

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Literature Corpus work
62d6d542-ec0e-56e5-85d7-351b7733558a
DOI
10.21203/rs.3.rs-8955297/v1
Open publication

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The methylation of the RANKL/OPG system is involved in fluorosis, and the effect of betaine supplementationDOI 10.21203/rs.3.rs-8955297/v1
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