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Analysis of anti-osteoporosis function of chlorogenic acid by gene microarray profiling in ovariectomy rat model

27 Jul 2018

Abstract excerpt

The aim of the present study was to clarify the effect of chlorogenic acid (CGA) on estrogen deficiency-induced osteoporosis based on micro-computed tomography (micro-CT) and potential mechanism of gene regulation via microarray profiling. Eighteen female Sprague–Dawley rats were divided randomly into sham-operated group, ovariectomy (OVX) plus saline vehicle group, and OVX plus CGA treatment group (CGA at 45...

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PMID: 30054432
DOI: 10.1042/bsr20180775

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