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Article

Frequent Dysregulation of the c-maf Proto-Oncogene at 16q23 by Translocation to an Ig Locus in Multiple Myeloma

1998-06-15

Abstract excerpt

Dysregulation of oncogenes by translocation to an IgH (14q32) or IgL (κ, 2p11 or λ, 22q11) locus is a frequent event in the pathogenesis of B-cell tumors. Translocations involving an IgH locus and a diverse but nonrandom array of chromosomal loci occur in most multiple myeloma (MM) tumors even though the translocations often are not detected by conventional cytogenetic analysis. In a continuing analysis of translo...

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Identifiers and source

Literature Corpus work
62c7207c-9e26-5305-9579-c2867d7eadd5
DOI
10.1182/blood.v91.12.4457.412k48_4457_4463
Open publication

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Frequent Dysregulation of the c-maf Proto-Oncogene at 16q23 by Translocation to an Ig Locus in Multiple MyelomaDOI 10.1182/blood.v91.12.4457.412k48_4457_4463
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