Article

Genomic Entropy confers an aggressive Phenotype in Mesothelioma

2026-06-05

Abstract excerpt

<title>Abstract</title> <p>Exposure to asbestos is the primary cause of mesothelioma, however the processes underpinning its initiation and evolutionary trajectory remain elusive. To address this knowledge gap, we conducted whole exome sequencing and phylogenetic analysis of 277 mesotheliomas. Using multidimensional Dirichlet process clustering we inferred phylogenies, uncovering mutation order dominated by early...

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Literature Corpus work: 629cddda-6bfb-5e3c-933f-bf0d05825328
DOI: 10.21203/rs.3.rs-8874509/v1

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