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Microinjection-based Single-Cell Toxicological Assessment Reveals How Physiological Levels of PFOS Impair Oocyte Maturation and Developmental Competence

2026-05-29

Abstract excerpt

Perfluorooctanesulfonic acid (PFOS) is a persistent environmental contaminant widely detected in human serum and follicular fluid and has been associated with reduced implantation rates and female fertility. However, its direct effects on mammalian oocyte maturation remain poorly understood. Here, we developed a microinjection-based single-oocyte toxicological assay to directly evaluate how physiologically relevan...

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Literature Corpus work
6268069f-b20c-5fbb-9f44-c4c74cdbbf55
DOI
10.64898/2026.05.26.727938
Open publication

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Microinjection-based Single-Cell Toxicological Assessment Reveals How Physiological Levels of PFOS Impair Oocyte Maturation and Developmental CompetenceDOI 10.64898/2026.05.26.727938
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