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BaP exposure causes oocyte meiotic arrest and fertilization failure to weaken female fertility

13 Sept 2017

Abstract excerpt

Benzo[a]pyrene (BaP) is a ubiquitous environmental pollutant and carcinogen that is frequently found in particulate matter, with a diameter of ≤ 2.5 μm (PM2.5). It has been reported to interrupt the normal reproductive system, but the exact molecular basis has not been clearly defined. To understand the underlying mechanisms regarding how BaP exposure disrupts female fertility, we evaluated oocyte quality by...

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PMID: 28904021
DOI: 10.1096/fj.201700514r

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