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Toxicant effects on mammalian oocyte mitochondria†

7 Jan 2021

Abstract excerpt

Oocyte mitochondria are unique organelles that establish a founder population in primordial germ cells (PGCs). As the oocyte matures in the postnatal mammalian ovary during folliculogenesis it increases exponentially in volume, and the oocyte mitochondria population proliferates to about 100 000 mitochondria per healthy, mature murine oocyte. The health of the mature oocyte and subsequent embryo is highly...

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PMID: 33412584
DOI: 10.1093/biolre/ioab002

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