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Bisphenol Z exposure inhibits oocyte meiotic maturation by rupturing mitochondrial function

11 Apr 2024

Abstract excerpt

The use of bisphenol A (BPA) has been restricted due to its endocrine-disrupting effects. As a widely used alternative to BPA today, environmental levels of bisphenol Z (BPZ) continue to rise and accumulate in humans. Oocyte quality is critical for a successful pregnancy. Nevertheless, the toxic impacts of BPZ on the maturation of mammalian oocytes remain unexplored. Therefore, the impacts of BPZ and BPA on...

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PMID: 38608383
DOI: 10.1016/j.ecoenv.2024.116312

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