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Isotretinoin use is associated with persistent alterations in male reproductive function

2026-07-27

Abstract excerpt

<h4>Background</h4> Isotretinoin (ISO) is a systemic retinoid widely used for the treatment of acne vulgaris , yet its potential effects on male reproductive function remain unclear with previous studies reporting inconsistent findings. <h4>Methods and findings</h4> We conducted a multi-model study combining data from the Danish Young Men Study (DYMS) cohort with ex vivo cultured human testis tissue and an i...

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Literature Corpus work
61f9ce02-511b-58ca-b5b0-56278858ba66
DOI
10.64898/2026.07.22.26356991
Open publication

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Isotretinoin use is associated with persistent alterations in male reproductive functionDOI 10.64898/2026.07.22.26356991
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