Is There a Reproductive Safety Risk in Male Patients Treated with Acitretin (Neotigason<sup>®</sup>/Soriatane<sup>®</sup>)?

Abstract excerpt

Review of preclinical data including genotoxicity assays and a male rat reproduction toxicology study demonstrates that acitretin (Neotigason)/Soriatane) does not affect the reproductive outcome in naive females mated with treated males. Prospective studies of teratogenic risk or impairment of fertility cannot be ethically conducted in humans. However, it is highly unlikely that any fetal malformation could be...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Antioxidant Activity and Oxidative Stress
• Share to Retinal Development and Disorders
• Share to Retinoids in leukemia and cellular processes