Article

m5C RNA modiﬁcation upregulates E2F1 expression dependently on YBX1 phase separation and promotes tumor progression in ovarian cancer

2023-07-25

Abstract excerpt

5-methylcytosine (m 5 C) is a common RNA modification that modulates gene expression at the post-transcriptional level, but the cross-talk between m 5 C RNA modification and biomolecule condensation as well as transcription factor-mediated transcriptional regulation in ovarian cancer remains poorly understood. In this study, we uncover that the RNA methytransferase NSUN2 facilitates m 5 C modification of mRNA and...

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Identifiers and source

Literature Corpus work: 618f487e-0ef2-59ab-b087-9ec2ddda87fa
DOI: 10.21203/rs.3.rs-3124825/v1

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m5C RNA modiﬁcation upregulates E2F1 expression dependently on YBX1 phase separation and promotes tumor progression in ovarian cancerDOI 10.21203/rs.3.rs-3124825/v1Read

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