Article

Systemic Factors Affect Bone Health in SMA Type II Patients and a Mouse Model of SMA

2025-02-05

Abstract excerpt

<h4>ABSTRACT</h4> Spinal muscular atrophy (SMA) is a rare developmental disorder affecting multiple tissues. Among the non-central nervous system tissues implicated in SMA is the skeletal system, including bone and cartilage. Low bone mineral density, increased numbers of fractures of the long bones and vertebra, hip pain, and scoliosis have been reported across the spectrum of SMA patients. While lack of ambulat...

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Literature Corpus work: 610dd68e-4dc4-54b7-8a5d-5d7f7d0444c6
DOI: 10.1101/2025.02.05.636673

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