Article

Alterations in Bone Mineral Density in Children with Spinal Muscular Atrophy under Nusinersen Treatment

2026-06-11

Abstract excerpt

<title>Abstract</title> <p>Purpose Children with spinal muscular atrophy (SMA) commonly exhibit low bone mineral density (BMD) during the natural disease course. This study aimed to investigate alterations in BMD and factors that are independently associated with BMD Z scores in patients with SMA types 2 and 3 treated with nusinersen. Methods This retrospective cohort study included 65 children with SMA types 2...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 87a50c33-5ae9-5535-909b-a1db612eec6a
DOI: 10.21203/rs.3.rs-9898893/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Alterations in Bone Mineral Density in Children with Spinal Muscular Atrophy under Nusinersen TreatmentDOI 10.21203/rs.3.rs-9898893/v1Read

Management of Spinal Muscular Atrophy in the Adult Population.Semantic proximity Read

Assessment of motor function and nutritional status in children with spinal muscular atrophy treated with nusinersen after loading period in western ChinaSemantic proximity Read

The Effects of Nusinersen Treatment on Respiratuar Status of Children with Spinal Muscular AtrophySemantic proximity Read

Bone Mineral Density and its Influencing Factors in Chinese Children with Spinal Muscular Atrophy types 2 and 3Semantic proximity Read

Systemic Factors Affect Bone Health in SMA Type II Patients and a Mouse Model of SMASemantic proximity Read

Disease Modifying Therapies for the Management of Children with Spinal Muscular Atrophy (5q SMA): An Update on the Emerging Evidence.Semantic proximity Read

Decision-making and challenges within the evolving treatment algorithm in spinal muscular atrophy: a clinical perspective.Semantic proximity Read

Respiratory effects of nusinersen treatment in pediatric patients with spinal muscular atrophy types 2 and 3Semantic proximity Read

Deficiencies in the medical care of SMA: evidence from a nationwide patient registry in GermanySemantic proximity Read

Effect of nusinersen after three years of treatment in 61 young children with SMA type 1 or 2: a French real-life observational studySemantic proximity Read

Motor function in type 2 and 3 SMA patients treated with Nusinersen: a critical review and meta-analysisSemantic proximity Read

Effect of nusinersen after 3 years of treatment in 57 young children with SMA in terms of SMN2 copy number or type.Semantic proximity Read