Article
Defining and identifying satellite cell-opathies within muscular dystrophies and myopathies.
Experimental cell research - 1 Feb 2022
Ganassi Massimo, Muntoni Francesco, Zammit Peter S
Abstract excerpt
Muscular dystrophies and congenital myopathies arise from specific genetic mutations causing skeletal muscle weakness that reduces quality of life. Muscle health relies on resident muscle stem cells called satellite cells, which enable life-course muscle growth, maintenance, repair and regeneration. Such tuned plasticity gradually diminishes in muscle diseases, suggesting compromised satellite cell function. A...
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