Article

Human intestinal enteroids with inducible neurogenin-3 expression as a novel model of gut hormone secretion

2019-03-16

Abstract excerpt

<h4>Background</h4> Enteroendocrine cells (EECs) are specialized epithelial cells that produce molecules vital for intestinal homeostasis, but due to their limited numbers, in-depth functional studies have remained challenging. Human intestinal enteroids (HIEs) that are derived from intestinal crypt stem cells are a biologically relevant in vitro model of the intestinal epithelium. HIEs contain all intestinal ep...

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Literature Corpus work: 60f39234-748b-5d54-8a7e-76b46d1399e8
DOI: 10.1101/579698

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