Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Deriving functional human enteroendocrine cells from pluripotent stem cells

1 Jan 2018

Abstract excerpt

Enteroendocrine cells (EECs) are a minor cell population in the intestine yet they play a major role in digestion, satiety, and nutrient homeostasis. Recent development of human intestinal organoid models include EECs, but their rarity makes it difficult to study their formation and function. Here we used the EEC-inducting property of the transcription factor NEUROG3 in human pluripotent stem cell (PSC)-derived...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diet, Metabolism, and Disease
Share to Digestive system and related health
Share to Pancreatic function and diabetes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30143540
DOI: 10.1242/dev.165795

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Deriving functional human enteroendocrine cells from pluripotent stem cellsPMID 30143540Read ↗

Human intestinal enteroids with inducible neurogenin-3 expression as a novel model of gut hormone secretionSemantic proximity Read ↗

Unraveling Enteroendocrine Cell lineage dynamics and associated gene regulatory networks during intestinal developmentSemantic proximity Read ↗

Intestinal Organoids Generated from Human Pluripotent Stem CellsSemantic proximity Read ↗

Coordinated differentiation of human intestinal organoids with functional enteric neurons and vasculatureSemantic proximity Read ↗

ISX-9 manipulates endocrine progenitor fate revealing conserved intestinal lineages in mouse and human organoidsSemantic proximity Read ↗

Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system.Semantic proximity Read ↗

Organoid Models of Human Gastrointestinal Development and Disease.Semantic proximity Read ↗

Building additional complexity to in vitro-derived intestinal tissuesSemantic proximity Read ↗

Human Intestinal Organoids: Promise and ChallengeSemantic proximity Read ↗

Neural Crest Cell Implantation Restores Enteric Nervous System Function and Alters the Gastrointestinal Transcriptome in Human Tissue-Engineered Small IntestineSemantic proximity Read ↗

ISX-9 manipulates endocrine progenitor fate revealing conserved intestinal lineages in mouse and humanSemantic proximity Read ↗

Human Intestinal Tissue with Adult Stem Cell Properties Derived from Pluripotent Stem CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.