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Infant and adult human intestinal enteroids are morphologically and functionally distinct

2 Jul 2024

Abstract excerpt

ABSTRACT Human intestinal enteroids (HIEs) are gaining recognition as physiologically relevant models of the intestinal epithelium. While HIEs from adults are used extensively in biomedical research, few studies have used HIEs from infants. Considering the dramatic developmental changes that occur during infancy, it is important to establish models that represent infant intestinal characteristics and...

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PMID: 38953637
DOI: 10.1128/mbio.01316-24

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