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Article

ATG5 gene delivery by rAAV9 promotes doxorubicin-induced atrial fibrillation and structural remodeling

2024-07-02

Abstract excerpt

<title>Abstract</title> <p>Doxorubicin (DOX) is used as first-line chemotherapeutic drug in treating various cancers. However, patients with DOX administration are susceptible to atrial fibrillation (AF) with unknown mechanisms. Numerous previous studies have shown that autophagy plays an important role in the development of AF, but autophagy protein 5 (ATG5) in DOX-induced AF has still not been studied. Mice wer...

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Literature Corpus work
60ebb7b6-5856-5d5b-b9f5-b4eab67a52d1
DOI
10.21203/rs.3.rs-4537399/v1
Open publication

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ATG5 gene delivery by rAAV9 promotes doxorubicin-induced atrial fibrillation and structural remodelingDOI 10.21203/rs.3.rs-4537399/v1
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