Article

Validation of a Non-invasive Prenatal Test for Fetal RhD, C, c, E, Kell and FyA Antigens

2023-03-20

Abstract excerpt

We developed and validated a next generation sequencing (NGS) based NIPT assay using quantitative counting template (QCT) technology to detect RhD, C, c, E, Kell, and Fy a fetal antigen genotypes in the diverse U.S. population. The assay quantifies paternally derived fetal antigen cell-free DNA molecules after calibration to fetal fraction and a reference gene. The assay correctly determined fetal antigen status f...

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Literature Corpus work: 60cf9ff9-f325-50e4-a0b5-05a2ccfbc2f9
DOI: 10.1101/2023.03.16.23287355

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