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Article

Validation of a non-invasive prenatal test for fetal RhD, C, c, E, K and Fya antigens.

Scientific reports - 7 Aug 2023

Alford Brian, Landry Brian P, Hou Sarah, Bower Xavier, Bueno Anna M, Chen Drake, Husic Brooke, Cantonwine David E, McElrath Thomas F, Carozza Jacqueline A, Wynn Julia, Hoskovec Jennifer, Gray Kathryn J

Abstract excerpt

We developed and validated a next generation sequencing-(NGS) based NIPT assay using quantitative counting template (QCT) technology to detect RhD, C, c, E, K (Kell), and Fya (Duffy) fetal antigen genotypes from maternal blood samples in the ethnically diverse U.S. population. Quantitative counting template (QCT) technology is utilized to enable quantification and detection of paternally derived fetal antigen...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37550335
DOI: 10.1038/s41598-023-39283-3
PMCID: PMC10406947

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