Article

Gli1 regulates the postnatal acquisition of peripheral nerve architecture

2021-09-16

Abstract excerpt

<h4>ABSTRACT</h4> Peripheral nerves are organized into discrete cellular compartments. Axons, Schwann cells (SCs), and endoneurial fibroblasts (EFs) reside within the endoneurium and are surrounded by the perineurium - a cellular sheath comprised of layers of perineurial glia (PNG). SC secretion of Desert Hedgehog (Dhh) regulates this organization. In Dhh nulls, the perineurium is deficient and the endoneurium is...

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Literature Corpus work: 60b8da1a-09e1-59f3-8583-e7e70b902315
DOI: 10.1101/2021.09.14.460314

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