Article

The role of the 3' untranslated region of tissue factor mRNA in its post-transcriptional regulation

2017-01-01

Abstract excerpt

Tissue factor (TF), an initiator of blood coagulation cascade, is not expressed in resting monocytes/macrophages but can be induced by LPS, providing a link between sepsis and thrombosis. In contrast, TF is highly expressed constitutively by MDA-MB-231 breast cancer cells. Our group has previously demonstrated that the stability of LPS-induced TF mRNA in macrophages is regulated by a complex involving the RNA bind...

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Literature Corpus work: 608eb823-3b9d-51be-8685-516df9c11cf1
DOI: 10.25560/67961

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