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Article

A 40-bp RNA element that mediates stabilization of vascular endothelial growth factor mRNA by HuR.

The Journal of biological chemistry - 19 Apr 2002

Goldberg-Cohen Ilana, Furneauxb Henry, Levy Andrew P

Abstract excerpt

VEGF is a critical mediator of hypoxia-induced angiogenesis in numerous physiological and pathophysiological conditions. The hypoxic induction of VEGF is due in large part to an increase in the stability of its mRNA. We recently demonstrated that the stabilization of VEGF mRNA by hypoxia is dependent upon the RNA-binding protein HuR. This report describes the identification of a 40-bp functional HuR binding site...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11834731
DOI: 10.1074/jbc.M108703200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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A 40-bp RNA element that mediates stabilization of vascular endothelial growth factor mRNA by HuR.PMID 11834731Read ↗

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Mutant copper-zinc superoxide dismutase associated with amyotrophic lateral sclerosis binds to adenine/uridine-rich stability elements in the vascular endothelial growth factor 3'-untranslated region.Semantic proximity Read ↗

Posttranscriptional regulation of the breast cancer susceptibility gene BRCA1 by the RNA binding protein HuR.Semantic proximity Read ↗

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Alternative polyadenylation variants of the RNA binding protein, HuR: abundance, role of AU-rich elements and auto-Regulation.Semantic proximity Read ↗

Hu antigen R (HuR) is a positive regulator of the RNA-binding proteins TDP-43 and FUS/TLS: implications for amyotrophic lateral sclerosis.Semantic proximity Read ↗

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