Article
The safety and efficacy of Ultrasound Histotripsy and human pluripotent stem cell-derived hepatic spheroid implantation as a potential therapy for treatment of congenital metabolic liver disease: assessment in an immunocompetent rodent model
2024-11-11
Abstract excerpt
<h4>Background</h4> Liver disease secondary to an inborn or genetic error of metabolism is a rare group of conditions often associated with chronic ill health and reduced survival. Curative treatment is mainly limited to liver transplantation with major long-term risks. Cell therapy is a promising alternative, but current approaches are ineffective. <h4>Aim</h4> To develop histotripsy, a non-invasive high intens...
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Identifiers and source
- Literature Corpus work
- 608a4bab-bb6f-5fdb-b88a-9731dccae34a
- DOI
- 10.1101/2024.11.08.622652