Article
SnoRNA signatures in cartilage ageing and osteoarthritis
2020-04-02
Abstract excerpt
<h4>ABSTRACT</h4> <h4>Objectives</h4> Osteoarthritis (OA) presents as a change in the chondrocyte phenotype and an imbalance between anabolic and catabolic processes. Age affects its onset and progression. Small nucleolar RNAs (SnoRNAs) direct chemical modification of RNA substrates to fine-tune spliceosomal and rRNA function, accommodating changing requirements for splicing and protein synthesis during health a...
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Identifiers and source
- Literature Corpus work
- d7069a10-b4bf-5778-9466-4a0dc1a449f6
- DOI
- 10.1101/2020.04.01.019505