Article

The ferroxidase HEPHaestin in Lung cancer: Pathological Significance and Prognostic Value

2021-01-25

Abstract excerpt

Iron is a fundamental nutrient utilized by living cells to support several key cellular processes. Despite its paramount role to sustain cell survival, excess of labile iron availability can inflict severe cell damage via reactive oxygen species generation which, in turn, can promote neoplastic transformation. The lung is particularly sensitive to iron-induced oxidative stress, given the high oxygen tensions herei...

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Literature Corpus work: 60619c96-36d7-5ca0-970b-130c63b41b88
DOI: 10.1101/2021.01.22.21250298

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