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Article

Knockdown of NADK promotes LUAD ferroptosis via NADPH/FSP1 axis

3 May 2024

Abstract excerpt

Abstract Background Lung cancer is a serious threat to human health and is the first leading cause of cancer death. Ferroptosis, a newly discovered form of programmed cell death associated with redox homeostasis, is of particular interest in the lung cancer, given the high oxygen environment of lung cancer. NADPH has reducing properties and therefore holds the potential to resist ferroptosis. Resistance to...

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PMID: 38700533
DOI: 10.1007/s00432-024-05752-z

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