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Article

Targeting Nrf2/PHKG2 axis to enhance radiosensitivity in NSCLC

21 Aug 2024

Abstract excerpt

While ferroptosis shows promise in anti-cancer strategy, the molecular mechanisms behind this process remain poorly understood. Our research aims to highlight the regulation of radiotherapy-induced ferroptosis in non-small cell lung cancer (NSCLC) via the NRF2/PHKG2 axis-mediated mechanism. To identify ferroptosis-associated genes associated with radioresistance in NSCLC, this study employed high-throughput...

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PMID: 39169204
DOI: 10.1038/s41698-024-00629-3

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