Article

A Proteomics-Informed Geometric Framework for Identifiability and Panel Design in Genome-Scale Metabolic Networks

2026-06-12

Abstract excerpt

<title>Abstract</title> <p>Genome-scale metabolic models provide a stoichiometric description of biochemical networks, yet most analytical frameworks remain data- or flux-centric, implicitly assuming full observability or well-defined flux states. Under realistic experimental conditions, metabolomics measurements capture only a sparse and condition-dependent subset of metabolites, raising a more fundamental quest...

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Literature Corpus work: 6039495d-c192-5a19-a9ec-715435ebf49f
DOI: 10.21203/rs.3.rs-8929972/v2

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