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Article

The antihistamine deptropine induces hepatoma cell death through blocking autophagosome-lysosome fusion

2020-05-07

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Autophagy is generally defined as a lysosome-dependent mechanism that degrades cytosolic proteins and organelles at the basal level. Recent studies focused on developing autophagy inhibitors for cancer treatment. Some antihistamines exhibited significant antitumor activity alone or in combination with other therapies in in vitro and clinical studies. However, th...

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Identifiers and source

Literature Corpus work
6030aa6e-257c-5f0a-ae10-2becc74c8bf3
DOI
10.21203/rs.3.rs-26426/v1
Open publication

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The antihistamine deptropine induces hepatoma cell death through blocking autophagosome-lysosome fusionDOI 10.21203/rs.3.rs-26426/v1
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