Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Natural small-molecule enhancers of autophagy induce autophagic cell death in apoptosis-defective cells

1 Jul 2014

Abstract excerpt

Resistance of cancer cells to chemotherapy is a significant problem in oncology, and the development of sensitising agents or small-molecules with new mechanisms of action to kill these cells is needed. Autophagy is a cellular process responsible for the turnover of misfolded proteins or damaged organelles, and it also recycles nutrients to maintain energy levels for cell survival. In some apoptosis-resistant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Berberine and alkaloids research
Share to Bioactive natural compounds

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24981420
DOI: 10.1038/srep05510

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Natural small-molecule enhancers of autophagy induce autophagic cell death in apoptosis-defective cellsPMID 24981420Read ↗

Targeting Autophagy with Natural Products as a Potential Therapeutic Approach for CancerSemantic proximity Read ↗

Molecular Insights into the Multifunctional Role of Natural Compounds: Autophagy Modulation and Cancer PreventionSemantic proximity Read ↗

Elaborating the Role of Natural Products-Induced Autophagy in Cancer Treatment: Achievements and Artifacts in the State of the ArtSemantic proximity Read ↗

New Visions on Natural Products and Cancer Therapy: Autophagy and Related Regulatory PathwaysSemantic proximity Read ↗

Small‐Molecule Regulators of Autophagy and Their Potential Therapeutic ApplicationsSemantic proximity Read ↗

Phytochemicals as potent modulators of autophagy for cancer therapySemantic proximity Read ↗

Autophagy-modulating phytochemicals in cancer therapeutics: Current evidences and future perspectivesSemantic proximity Read ↗

Autophagy: Mechanisms and Therapeutic Potential of Flavonoids in CancerSemantic proximity Read ↗

Natural Compounds As Modulators of Non-apoptotic Cell Death in Cancer CellsSemantic proximity Read ↗

Plant natural compounds: targeting pathways of autophagy as anti‐cancer therapeutic agentsSemantic proximity Read ↗

Advances in indole-containing alkaloids as potential anticancer agents by regulating autophagySemantic proximity Read ↗

Antioxidants activities of phytochemicals perspective modulation of autophagy and apoptosis to treating cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.