Article

Uncovering Transcriptional Dark Matter via Gene Annotation Independent Single-Cell RNA Sequencing Analysis

2020-08-03

Abstract excerpt

<h4>ABSTRACT</h4> Single-cell RNA sequencing (scRNA-seq) enables the study of cell biology with high resolution. scRNA-seq expression analyses rely on the availability of a high quality annotation of genes in the genome. Yet, as we show here with scRNA-seq experiments and analyses spanning human, mouse, chicken, mole rat, lemur and sea urchin, gene annotations often fail to cover the full transcriptome of every c...

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Literature Corpus work: 602a2ff9-ba55-559d-9aff-377fcb8036c1
DOI: 10.1101/2020.07.31.229575

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