Article
Meta-analysis of genome-wide association data identifies a risk locus for major mood disorders on 3p21.1.
Nature genetics - 1 Feb 2010
McMahon Francis J, Akula Nirmala, Schulze Thomas G, Muglia Pierandrea, Tozzi Federica, Detera-Wadleigh Sevilla D, Steele C J M, Breuer René, Strohmaier Jana, Wendland Jens R, Mattheisen Manuel, Mühleisen Thomas W, Maier Wolfgang, Nöthen Markus M, Cichon Sven, Farmer Anne, Vincent John B, Holsboer Florian, Preisig Martin, Rietschel Marcella
Abstract excerpt
The major mood disorders, which include bipolar disorder and major depressive disorder (MDD), are considered heritable traits, although previous genetic association studies have had limited success in robustly identifying risk loci. We performed a meta-analysis of five case-control cohorts for ma...
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