Article

A survivin-driven tumour-activatable minicircle system for prostate cancer theranostics

2020-06-26

Abstract excerpt

Gene vectors driven by tumour-specific promoters to express reporter genes and therapeutic genes are an emerging approach for improved cancer diagnosis and treatment. Minicircles (MCs) are shortened plasmids stripped of prokaryotic sequences and have potency and safety characteristics that are beneficial for clinical translation. We previously developed survivin-driven, tumour-activatable MCs for cancer detection...

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Literature Corpus work: 6018ed87-0fff-52df-9d90-39bb3f465f50
DOI: 10.1101/2020.06.25.171645

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