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Article

Prostasomes as a source of diagnostic biomarkers for prostate cancer

31 Mar 2016

Abstract excerpt

New biomarkers are needed to improve the diagnosis of prostate cancer. Similarly to healthy cells, prostate epithelial cancer cells produce extracellular vesicles (prostasomes) that can be isolated from seminal fluid, urine, and blood. Prostasomes contain ubiquitously expressed and prostate-specific membrane and cytosolic proteins, as well as RNA. Both quantitative and qualitative changes in protein, mRNA, long...

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PMID: 27035806
DOI: 10.1172/jci81128

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