Article

Depletion of <i>ALMS1</i> affects TGF-β signalling pathway and downstream processes such as cell migration and adhesion capacity

2021-12-19

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> ALMS1 is a ubiquitous gene associated with Alström syndrome (ALMS). The main symptoms of ALMS affect multiple organs and tissues, generating at last, multi-organic fibrosis in the lungs, kidneys and liver. TGF-β is one of the main pathways implicated in fibrosis, controlling the cell cycle, apoptosis, cell migration, cell adhesion and epithelial-mesenchymal transition (EMT)....

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Literature Corpus work: 5fea6bea-90c8-52da-aa3a-b66a4866c4b6
DOI: 10.1101/2021.12.19.473196

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Depletion of <i>ALMS1</i> affects TGF-β signalling pathway and downstream processes such as cell migration and adhesion capacityDOI 10.1101/2021.12.19.473196Read

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