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Platelet transcriptome identifies progressive markers and potential therapeutic targets in chronic myeloproliferative neoplasms

1 Oct 2021

Abstract excerpt

Predicting disease progression remains a particularly challenging endeavor in chronic degenerative disorders and cancer, thus limiting early detection, risk stratification, and preventive interventions. Here, profiling the three chronic subtypes of myeloproliferative neoplasms (MPNs), we identify the blood platelet transcriptome as a proxy strategy for highly sensitive progression biomarkers that also enables...

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PMID: 34755136
DOI: 10.1016/j.xcrm.2021.100425

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