Article

5-HTT polymorphisms in congenital central hypoventilation syndrome contribute to a modified resting CO2 set point

2026-01-30

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> . Central respiratory chemoreceptors are not definitively identified, but the retrotrapezoid nucleus is the main center whose absence is characteristic of congenital central hypoventilation syndrome (CCHS). Intense chemosensory stimuli activate circuits that are wake- or attention-promoting, such as the raphe, which modulates chemoreflexes. The main objective...

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Literature Corpus work: 5fc842ea-e73e-5155-8579-3cfdc8d2f9a8
DOI: 10.21203/rs.3.rs-7860440/v1

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