Article

Uncovering uncharacterized binding of transcription factors from ATAC-seq footprinting data

2023-10-29

Abstract excerpt

Transcription factors (TFs) are crucial epigenetic regulators, which enable cells to dynamically adjust gene expression in response to environmental signals. Computational procedures like digital genomic footprinting on chromatin accessibility assays such as ATACseq can be used to identify bound TFs in a genome-wide scale. This method utilizes short regions of low accessibility signals due to steric hindrance of D...

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Literature Corpus work: 5f883cd5-6084-5581-87e2-544b8be01542
DOI: 10.1101/2023.10.26.563982

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